In this paper, tests were made so the test form was printed in larger circulation in real conditions on printing machine. Tests were performed on the elements of the test forms where it was possible to calculate the dot gain of screen value, to determine the density fluctuations in coloration and CIE L* a* b* values of the gray balance, and with whom it is possible to establish a visual print quality. Visual perception of print quality on different profiles was made on half-tone images. Specimens were taken from different parts of the circulation and samples were taken from twenty different runs of 13000 prints. Printing was done respecting the recommendations of the international ISO standards. Based on scientific analysis of separate samples the density of coloration and dot gain was obtained and oscillations of the gray balance throughout the print run were found. Also the recommendations of profiles for half-tone colour images as well as the recommendations of tolerance density that is not prescribed by international standards were given. Synthesizing research results gave new findings about the quality of newspaper printing.