There is a great incidence of digestive tumors, five of the ten most common carcinoma are ones localized in the digestive tract. The aim of modern gastroenterological diagnostics is early detection of tumorous esophageal, gastric and colon changes, if possible in their precancerous or T1m stage, when endoscopic removal of tumors (EEP, EMR, ESD) is still simple, reliable and cost-efficient. In order to evaluate the diagnostic procedure, its accuracy and efficiency, we created this retrospective study. In our study we processed patients that had undergone outpatient based workup with prompt endoscopic, pathohistological, mini radial ultrasound and multi-slice CT (MSCT) diagnostics. Verified esophageal (29), gastric (57) and colon (69) tumorous processes have been removed either endoscopically (45) or through surgical resection (110). Exceptionally high level of correlation of mini radial endoscopic ultrasound determined dissemination degree (TN) with the PH verified disease stage confirms that mini radial endosonography is an excellent method in visualizing close structures as well as an useful one when analyzing structure and staging of tumorous esophageal, gastric and colon changes. By differentiating between T 1m, T 1sm, T2 andT3tumor stages, this diagnostic method allows for an appropriate patient selection when considering endoscopic procedures or surgical resection. For endoscopists and ultrasonographers this method is easily applicable and by making room for rational therapy selection, it makes great savings in the health system also enabling the patient to be treated with an optimal method according to the tumor dissemination degree. The results of this study encourage greater use of mini radial endosonography as well as a more frequent use of EMR as a method in treatment of T1m tumors of esophagus, stomach and colon. The accuracy of the primary tumor depth approximation is 93-97%, which makes this the method of choice when evaluating the degree of digestive tumors staging. With excellent tumor visualization, mini radial probe assists VIIendoscopic mucosal resection, making it more successful. Also, for a great deal of our patients, this method allows for a more precise, reliable and almost always, a less aggressive approach