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doctoral thesis
Identification and characterization of transposable elements in sponges (Porifera)
Zagreb: University of Zagreb, Faculty of Science, 2020. urn:nbn:hr:217:082440
Kuzman, Maja
University of Zagreb
Faculty of Science
Department of Biology

Cite this document

Kuzman, M. (2020). Identification and characterization of transposable elements in sponges (Porifera) (Doctoral thesis). Zagreb: University of Zagreb, Faculty of Science. Retrieved from https://urn.nsk.hr/urn:nbn:hr:217:082440

Kuzman, Maja. "Identification and characterization of transposable elements in sponges (Porifera)." Doctoral thesis, University of Zagreb, Faculty of Science, 2020. https://urn.nsk.hr/urn:nbn:hr:217:082440

Kuzman, Maja. "Identification and characterization of transposable elements in sponges (Porifera)." Doctoral thesis, University of Zagreb, Faculty of Science, 2020. https://urn.nsk.hr/urn:nbn:hr:217:082440

Kuzman, M. (2020). 'Identification and characterization of transposable elements in sponges (Porifera)', Doctoral thesis, University of Zagreb, Faculty of Science, accessed 20 April 2024, https://urn.nsk.hr/urn:nbn:hr:217:082440

Kuzman M. Identification and characterization of transposable elements in sponges (Porifera) [Doctoral thesis]. Zagreb: University of Zagreb, Faculty of Science; 2020 [cited 2024 April 20] Available at: https://urn.nsk.hr/urn:nbn:hr:217:082440

M. Kuzman, "Identification and characterization of transposable elements in sponges (Porifera)", Doctoral thesis, University of Zagreb, Faculty of Science, Zagreb, 2020. Available at: https://urn.nsk.hr/urn:nbn:hr:217:082440

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Metadata
TitleIdentification and characterization of transposable elements in sponges (Porifera)
Title (english)Identifikacija i karakterizacija pokretnih genetičkih elemenata u spužvama (Porifera)
AuthorMaja Kuzman
MentorKristian Vlahoviček (mentor)
Committee memberHelena Ćetković (predsjednik povjerenstva)
Committee memberRosa Karlić (član povjerenstva)
GranterUniversity of Zagreb
Faculty of Science
(Department of Biology)
Zagreb
Defense date and country2020-09-29, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Biology
Universal decimal classification
(UDC)		57 - Biological sciences. Physical anthropology. Biodiversity
Abstract
Transposable elements constitute a large portion of most eukaryotic genomes and play an important role in transcriptional regulation, shaping gene regulatory networks and genome evolution. Due to a lack of quality genome assemblies of non-model organisms, not much is known about the diversity, distribution and the role of transposable elements across Metazoa. In this thesis I present high quality genome assemblies for the sponge species Eunapius subterraneus and Suberites domuncula. I use computational genomics techniques to identify, characterize and compare transposable elements in the publicly available sponge genomes and in-house assembled genomes by analysing the abundance and conservation of the transposable elements in different sponge species. I assess the impact of transposable elements on the evolution of the host genomes by analysing their contribution to genome organization and correlation with gene expression. Finally, I present a catalog of the homologs of piRNA pathway in sponges and analyse their transcriptional activity.
Abstract (english)
Prijenosni genetički elementi (transpozoni) sačinjavaju velik dio većine eukariotskih genoma i igraju važnu ulogu u regulaciji transkripcije, oblikovanju regulatornih mreža gena i evoluciji genoma. Zbog nedostatka kvalitetno sklopljenih genoma ne-modelnih organizama, ne zna se mnogo o raznolikosti, rasprostranjenosti i ulozi transpozona u skupini Metazoa. U ovom radu predstavljam visokokvalitetne sklopove genoma za vrste spužva Eunapius subterraneus i Suberites domuncula. Korištenjem tehnika računalne genomike identificiram, karakteriziram i uspoređujem pokretne elemente u javno dostupnim genomima spužvi i interno skupljenim genomima analizom brojnosti i očuvanja transpozona u različitim vrstama spužvi. Procjenjujem utjecaj transpozona na evoluciju genoma domaćina analizom njihovog doprinosa u organizaciji genoma i povezanosti s ekspresijom gena. Na kraju predstavljam katalog homologa piRNA puta u spužvama i analiziram njihovu transkripcijsku aktivnost.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:217:082440
Promotion2020
Study programmeTitle: Biology
Study programme type: university
Study level: postgraduate
Academic / professional title: doktor/doktorica znanosti, područje prirodnih znanosti, polje biologija (doktor/doktorica znanosti, područje prirodnih znanosti, polje biologija)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
RepositoryRepository of the Faculty of Science
Created on2020-10-27 10:06:33

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