Ciljana atenuacija virusa mumpsa na temelju virusnih faktora koji moduliraju mehanizme urođene imunosti

Jagušić, Maja

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doctoral thesis

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Targeted attenuation of mumps virus by viral factors that modulate the innate immune response

Maja Jagušić (2017)

University of Zagreb
Faculty of Food Technology and Biotechnology

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APA 6th Edition

Jagušić, M. (2017). Ciljana atenuacija virusa mumpsa na temelju virusnih faktora koji moduliraju mehanizme urođene imunosti (Doctoral thesis). Retrieved from https://urn.nsk.hr/urn:nbn:hr:159:936217

MLA 8th Edition

Jagušić, Maja. "Ciljana atenuacija virusa mumpsa na temelju virusnih faktora koji moduliraju mehanizme urođene imunosti." Doctoral thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2017. https://urn.nsk.hr/urn:nbn:hr:159:936217

Chicago 17th Edition

Jagušić, Maja. "Ciljana atenuacija virusa mumpsa na temelju virusnih faktora koji moduliraju mehanizme urođene imunosti." Doctoral thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2017. https://urn.nsk.hr/urn:nbn:hr:159:936217

Harvard

Jagušić, M. (2017). 'Ciljana atenuacija virusa mumpsa na temelju virusnih faktora koji moduliraju mehanizme urođene imunosti', Doctoral thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, accessed 18 July 2019, https://urn.nsk.hr/urn:nbn:hr:159:936217

Vancouver

Jagušić M. Ciljana atenuacija virusa mumpsa na temelju virusnih faktora koji moduliraju mehanizme urođene imunosti [Doctoral thesis]. Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology; 2017 [cited 2019 July 18] Available at: https://urn.nsk.hr/urn:nbn:hr:159:936217

IEEE

M. Jagušić, "Ciljana atenuacija virusa mumpsa na temelju virusnih faktora koji moduliraju mehanizme urođene imunosti", Doctoral thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, Zagreb, 2017. Available at: https://urn.nsk.hr/urn:nbn:hr:159:936217

Cite this item: https://urn.nsk.hr/urn:nbn:hr:159:936217

Metadata

Title	Ciljana atenuacija virusa mumpsa na temelju virusnih faktora koji moduliraju mehanizme urođene imunosti
Title (english)	Targeted attenuation of mumps virus by viral factors that modulate the innate immune response
Author	Maja Jagušić
Mentor	Maja Šantak (mentor)
Committee member	Višnja Gaurina-Srček (predsjednik povjerenstva)
Granter	University of Zagreb Faculty of Food Technology and Biotechnology Zagreb
Defense date and country	2017-11-17, Croatia
Scientific / art field, discipline and subdiscipline	BIOTECHNICAL SCIENCES Biotechnology
Universal decimal classification (UDC)	612 APPLIED SCIENCES. MEDICINE. TECHNOLOGY Physiology
Abstract	Cilj ovog istraživanja bio je karakterizirati indukciju mehanizama urođene imunosti na viruse mumpsa različitog stupnja atenuacije. Kao virusni faktori koji mogu modulirati te mehanizme ispitane su defektne intereferirajuće čestice prisutne u virusnoj suspenziji te ekspresija virusnog proteina V. Proizašla saznanja primijenjena su za ciljanu atenuaciju divljeg soja virusa mumpsa kao modela za razvoj novog atenuiranog cjepiva.
Abstract (english)	The aim of this study was to characterize the innate immune responses to mumps viruses of different attenuation level. Defective interfering particles present in the viral suspensions and expression of the viral V protein were examined as viral factors critical for modulation of these responses. The gained knowledge was further applied for targeted attenuation of a wild-type mumps virus as a model for development of a new attenuated vaccine.
Keywords
Keywords (english)
Language	croatian
URN:NBN	urn:nbn:hr:159:936217
Study programme	Title: Biotehnologija i bioprocesno inženjerstvo Study programme type: sveučilišni Study level: poslijediplomski doktorski Academic / professional title: doktor/doktorica znanosti (doktor/doktorica znanosti)
Type of resource	Text
File origin	Born digital
Access conditions	Restricted access
Terms of use
Repository	Repository of the Faculty of Food Technology and Biotechnology
Created on	2018-05-18 11:22:31