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doctoral thesis
Utjecaj razine homocisteina i određenih vitamina B skupine na mineralnu gustoću kosti i biokemijske pokazatelje koštane pregradnje u žena
Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology, 2010. urn:nbn:hr:159:933532
Rumbak, Ivana
University of Zagreb
Faculty of Food Technology and Biotechnology

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Rumbak, I. (2010). Utjecaj razine homocisteina i određenih vitamina B skupine na mineralnu gustoću kosti i biokemijske pokazatelje koštane pregradnje u žena (Doctoral thesis). Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:159:933532

Rumbak, Ivana. "Utjecaj razine homocisteina i određenih vitamina B skupine na mineralnu gustoću kosti i biokemijske pokazatelje koštane pregradnje u žena." Doctoral thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2010. https://urn.nsk.hr/urn:nbn:hr:159:933532

Rumbak, Ivana. "Utjecaj razine homocisteina i određenih vitamina B skupine na mineralnu gustoću kosti i biokemijske pokazatelje koštane pregradnje u žena." Doctoral thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2010. https://urn.nsk.hr/urn:nbn:hr:159:933532

Rumbak, I. (2010). 'Utjecaj razine homocisteina i određenih vitamina B skupine na mineralnu gustoću kosti i biokemijske pokazatelje koštane pregradnje u žena', Doctoral thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, accessed 18 April 2024, https://urn.nsk.hr/urn:nbn:hr:159:933532

Rumbak I. Utjecaj razine homocisteina i određenih vitamina B skupine na mineralnu gustoću kosti i biokemijske pokazatelje koštane pregradnje u žena [Doctoral thesis]. Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology; 2010 [cited 2024 April 18] Available at: https://urn.nsk.hr/urn:nbn:hr:159:933532

I. Rumbak, "Utjecaj razine homocisteina i određenih vitamina B skupine na mineralnu gustoću kosti i biokemijske pokazatelje koštane pregradnje u žena", Doctoral thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, Zagreb, 2010. Available at: https://urn.nsk.hr/urn:nbn:hr:159:933532

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Metadata
TitleUtjecaj razine homocisteina i određenih vitamina B skupine na mineralnu gustoću kosti i biokemijske pokazatelje koštane pregradnje u žena
Title (english)The influence of homocysteine level and specific B vitamins on bone mineral density and biochemical markers of bone turnover in women
AuthorIvana Rumbak
MBZ: 267962
MentorIrena Colić Barić (mentor)
MBZ: 120646
Committee memberVladimir Mrša (predsjednik povjerenstva)
MBZ: 39525
GranterUniversity of Zagreb
Faculty of Food Technology and Biotechnology
Zagreb
Defense date and country2010-12-17, Croatia
Scientific / art field,
discipline and subdiscipline		BIOTECHNICAL SCIENCES
Food Technology
Universal decimal classification
(UDC)		577 - Biochemistry. Molecular biology. Biophysics
Abstract
U ovom istraživanju cilj je bio utvrditi razinu homocisteina (Hcy) obzirom na poznate rizične čimbenike, te povezanost između razine Hcy, statusa folata, vitamina B12 u krvi i mineralne gustoće kosti (BMD) u ispitanica dobi 45-65 godina (n=174). Od dijetetičkih parametara jedino je konzumacija kave bila povezana s koncentracijom Hcy (p<0,05). Između BMD i razine Hcy te statusa vitamina B12 i folata nije utvrđena korelacija. U ispitanica s blago povećanom razinom Hcy (n=59) koje su bile uključene u randomiziranu kontroliranu dvostruko maskiranu kliničku studiju, nakon 4 mjeseca uzimanja folne kiseline (800 μg/dan) došlo je do povećanja koncentracije folne kiseline i sniženja koncentracije Hcy u usporedbi s kontrolnom skupinom (p<0,05), ali ne i statistički značajne promjene koncentracija biokemijskih pokazatelja koštane pregradnje.
Abstract (english)
The aim of the study was to determine homocysteine (Hcy) level considering known risk factors for elevated Hcy level as well as relationship between Hcy level, folate and vitamin B12 status and bone mineral density (BMD) in women aged 45-65 (n=174). Coffee consumption was the only dietetic parameter associated with Hcy level (p<0,05). Results of this study suggest that Hcy, folate or vitamin B12 levels were not related to BMD. In double blind placebo controlled trial participants with mildly elevated Hcy level (n=59) showed significant increase of folate and vitamin B12 level and significant decrease in Hcy level after 4 months of folic acid supplementation (800 μg/day) compared with placebo group. Biochemical markers of bone turnover levels showed no statistically significant difference after intervention.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:159:933532
Promotion2011-07-03
Study programmeTitle: Nutrition
Study programme type: university
Study level: postgraduate
Academic / professional title: doktor znanosti/doktorica znanosti (doktor znanosti/doktorica znanosti)
Type of resourceText
File originBorn digital
Access conditionsAccess restricted to students and staff of home institution
Terms of useLicence In copyright icon
RepositoryRepository of the Faculty of Food Technology and Biotechnology
Created on2018-05-15 11:04:01

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