prikaz prve stranice dokumenta Apoptoticke promjene u kulturi životinjskih stanica i mehanizmi djelovanja endogenih i egzogenih faktora
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doctoral thesis
Apoptoticke promjene u kulturi životinjskih stanica i mehanizmi djelovanja endogenih i egzogenih faktora
Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology, 2010. urn:nbn:hr:159:478608
Radoševic, Kristina
University of Zagreb
Faculty of Food Technology and Biotechnology

Cite this document

Radoševic, K. (2010). Apoptoticke promjene u kulturi životinjskih stanica i mehanizmi djelovanja endogenih i egzogenih faktora (Doctoral thesis). Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:159:478608

Radoševic, Kristina. "Apoptoticke promjene u kulturi životinjskih stanica i mehanizmi djelovanja endogenih i egzogenih faktora." Doctoral thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2010. https://urn.nsk.hr/urn:nbn:hr:159:478608

Radoševic, Kristina. "Apoptoticke promjene u kulturi životinjskih stanica i mehanizmi djelovanja endogenih i egzogenih faktora." Doctoral thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2010. https://urn.nsk.hr/urn:nbn:hr:159:478608

Radoševic, K. (2010). 'Apoptoticke promjene u kulturi životinjskih stanica i mehanizmi djelovanja endogenih i egzogenih faktora', Doctoral thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, accessed 25 April 2024, https://urn.nsk.hr/urn:nbn:hr:159:478608

Radoševic K. Apoptoticke promjene u kulturi životinjskih stanica i mehanizmi djelovanja endogenih i egzogenih faktora [Doctoral thesis]. Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology; 2010 [cited 2024 April 25] Available at: https://urn.nsk.hr/urn:nbn:hr:159:478608

K. Radoševic, "Apoptoticke promjene u kulturi životinjskih stanica i mehanizmi djelovanja endogenih i egzogenih faktora", Doctoral thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, Zagreb, 2010. Available at: https://urn.nsk.hr/urn:nbn:hr:159:478608

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Metadata
TitleApoptoticke promjene u kulturi životinjskih stanica i mehanizmi djelovanja endogenih i egzogenih faktora
Title (english)Apoptotic changes in animal cell cultures and mechanisms of action of endogenous and exogenous factors
AuthorKristina Radoševic
MBZ: 255075
MentorZlatko Kniewald (mentor)
MBZ: 71903
Committee memberVišnja Gaurina Srcek (predsjednik povjerenstva)
MBZ: 206591
GranterUniversity of Zagreb
Faculty of Food Technology and Biotechnology
Zagreb
Defense date and country2010-12-10, Croatia
Scientific / art field,
discipline and subdiscipline		BIOTECHNICAL SCIENCES
Biotechnology
Universal decimal classification
(UDC)		576 - Cellular and subcellular biology. Cytology
Abstract
Pročišćeni i izolirani protein iz svinjskog mozga identificiran je kao kiseli fibroblastni faktor rasta. Sirovi ekstrakt svinjskog mozga ima pozitivni učinak na rast stanica u primarnoj kulturi ovarija i uterusa štakora te u CCO i CHO-K1 staničnim linijama. Ispitano je djelovanje 17-etinilestradiola i dietilstilbestrola na rast CCO i CHO-K1 stanica. Oba spoja, pri koncentracijama 1 μg/mL i veće, djeluju citotoksično. 17-Etinilestradiol inducira staničnu smrt procesom apoptoze, dok dietilstilbestrol inducira nekrozu u obje stanične linije.
Abstract (english)
Protein purified and isolated from porcine brain was identified as acidic fibroblast growth factor. Crude brain extract showed positive effect on cell in vitro proliferation in primary culture of rat's ovary and uterus cells as well as in CCO and CHO-K1 cell lines. Effect of 17-ethynylestradiol and diethylstilbestrol was investigated in CCO and CHO-K1 cells. Both compounds, in concentrations 1 μg/ml and higher, showed cytotoxic effect. 17-Ethynylestradiol induced cell death by apoptosis, while diethylstilbestrol induced necrosis in both cell lines.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:159:478608
Promotion2011-07-03
Study programmeTitle: Postgraduate PhD Study in Biotechnology and Bioprocess Engineering
Study programme type: university
Study level: postgraduate
Academic / professional title: doktor/doktorica znanosti (doktor/doktorica znanosti)
Type of resourceText
File originBorn digital
Access conditionsAccess restricted to students and staff of home institution
Terms of useLicence In copyright icon
RepositoryRepository of the Faculty of Food Technology and Biotechnology
Created on2018-05-15 10:10:59

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