prikaz prve stranice dokumenta Praćenje pretvorbe antihelmintika u vodenom okolišu i procjena ekotoksikološkoga djelovanja
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doctoral thesis
Praćenje pretvorbe antihelmintika u vodenom okolišu i procjena ekotoksikološkoga djelovanja
Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology, 2014. urn:nbn:hr:159:105295
Radman, Sanja
University of Zagreb
Faculty of Food Technology and Biotechnology

Cite this document

Radman, S. (2014). Praćenje pretvorbe antihelmintika u vodenom okolišu i procjena ekotoksikološkoga djelovanja (Doctoral thesis). Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:159:105295

Radman, Sanja. "Praćenje pretvorbe antihelmintika u vodenom okolišu i procjena ekotoksikološkoga djelovanja." Doctoral thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2014. https://urn.nsk.hr/urn:nbn:hr:159:105295

Radman, Sanja. "Praćenje pretvorbe antihelmintika u vodenom okolišu i procjena ekotoksikološkoga djelovanja." Doctoral thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, 2014. https://urn.nsk.hr/urn:nbn:hr:159:105295

Radman, S. (2014). 'Praćenje pretvorbe antihelmintika u vodenom okolišu i procjena ekotoksikološkoga djelovanja', Doctoral thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, accessed 16 April 2024, https://urn.nsk.hr/urn:nbn:hr:159:105295

Radman S. Praćenje pretvorbe antihelmintika u vodenom okolišu i procjena ekotoksikološkoga djelovanja [Doctoral thesis]. Zagreb: University of Zagreb, Faculty of Food Technology and Biotechnology; 2014 [cited 2024 April 16] Available at: https://urn.nsk.hr/urn:nbn:hr:159:105295

S. Radman, "Praćenje pretvorbe antihelmintika u vodenom okolišu i procjena ekotoksikološkoga djelovanja", Doctoral thesis, University of Zagreb, Faculty of Food Technology and Biotechnology, Zagreb, 2014. Available at: https://urn.nsk.hr/urn:nbn:hr:159:105295

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Metadata
TitlePraćenje pretvorbe antihelmintika u vodenom okolišu i procjena ekotoksikološkoga djelovanja
Title (english)Anthelmintics transformation monitoring in aqueous environment and evaluation of ecotoxic effects
AuthorSanja Radman
MentorTibela Landeka Dragičević (mentor)
Committee memberVeronika Kovač (predsjednik povjerenstva)
GranterUniversity of Zagreb
Faculty of Food Technology and Biotechnology
Zagreb
Defense date and country2014-04-24, Croatia
Scientific / art field,
discipline and subdiscipline		BIOTECHNICAL SCIENCES
Biotechnology
Universal decimal classification
(UDC)		60 - Biotechnology. Genetic engineering. Products of cloning
Abstract
U okviru disertacije provedena su istraživanja na odabranim antihelminticima (albendazol, febantel, levamisol, pirantel i prazikvantel) s ciljem određivanja produkata njihove pretvorbe u vodenom okolišu tijekom izlaganja sunčevom zračenju, te određivanja ekotoksičnosti na organizmima iz različitih razreda (bakterije Vibrio fischeri, alge Selenastrum capricornutum i planktonski račić Daphnia magna). Produkti pretvorbe dobiveni su izlaganjem uzoraka simuliranom zračenju i zračenju Sunca. Provedena je usporedba profila raspadanja matičnih molekula, te profil nastalih produkata. Analize su provedene tekućinskom kromatografijom sa spektrometrijom masa (LC–MS/MS), a identifikacija novonastalih produkata i određivanje njihove strukture točnim mjerenjem masa pomoću hibridnog analizatora kvadripol–brzinski s mjerenjem vremena preleta (eng. quadrupole–time–of flight, QqTOF). Dio istraživanja obuhvatio je ispitivanje utjecaja vodenog okoliša na stvaranje produkata te se pratio profil pretvorbe u vodama različitog sastava i koncentracija dodanih odabranih tvari.
Abstract (english)
In this paper work research on anthelmintics (albendazole, febantel, levamisole, pyrantel and praziquantel) was performed with aim to determine aqueous transformation products during sun irradiation and to determine ecotoxic effects on the different class membered organisms (Vibrio fischeri, Selenastrum capricornutum and Daphnia magna). Transformation products were gained exposing the sample to sun simulator irradiation and irradiation of the Sun, and the profile analogy of the decreasing parent compound and arising products were performed by analysis on liquid chromatography tandem mass spectrometry (LC–MS/MS) system. Identification and structural elucidation of newly araised products were carried out on hybride analyzer quadrupole–time–of flight (QqTOF) measuring the accurate mass. Part of research considered of investigation of the aqueous environment effect on arising products, and transformation profiles in water of a different composition and concentration of added matter were tracked.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:159:105295
Promotion2014-07-06
Study programmeTitle: Postgraduate PhD Study in Biotechnology and Bioprocess Engineering
Study programme type: university
Study level: postgraduate
Academic / professional title: doktor/doktorica znanosti (doktor/doktorica znanosti)
Type of resourceText
File originBorn digital
Access conditionsAccess restricted to students and staff of home institution
Terms of useLicence In copyright icon
RepositoryRepository of the Faculty of Food Technology and Biotechnology
Created on2018-05-17 11:59:21

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